Rune of Berkano
AchievementRebirthUnlock unknown
Achievement details
- Achievement number
- 95
- Description
- Unlocked a new item.
- Requirement
- Complete Purist (challenge #20)
How do you unlock Rune of Berkano?
In The Binding of Isaac, Rune of Berkano is unlocked by unlocking Purist (Challenge).
Structured pathSource-backed requirements are mapped into trackable steps.
Unlocked a new item.
What unlocking Rune of Berkano leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13