D12

ItemAfterbirthLocked

activeGame ID 386★★★★

How do you unlock D12?

In The Binding of Isaac, D12 is unlocked by earning the Hush completion mark as Cain (Character).

Structured pathSource-backed requirements are mapped into trackable steps.

[Before Repentance] Re-rolls all Rocks and Metal Blocks in the current room into other random obstacles. / [Repentance] Re-rolls most types of obstacles in the current room into other random obstacles.

D12 (Achievement)
- Cain (Character) → Hush (normal)
  1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
  2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
  3. Defeat Hush in Blue Womb. source
  - Cain (Character)

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What unlocking D12 leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13