Hemoptysis

ItemRepentanceLocked

passiveGame ID 726★★★★

How do you unlock Hemoptysis?

In The Binding of Isaac, Hemoptysis is unlocked by earning the Delirium completion mark as Tainted Azazel.

Structured pathSource-backed requirements are mapped into trackable steps.

Double-tapping a fire button causes Isaac to sneeze blood, dealing damage to enemies in front of him. Affected enemies are cursed and take more damage from Brimstone-like attacks.

Hemoptysis (Achievement)
- Tainted Azazel → Delirium (normal)
  1. Defeat Hush to unlock The Void. source
  2. A Void portal can appear after a major boss; defeating Hush guarantees one. source
  3. Defeat Delirium, the main boss of The Void. source
  - Tainted Azazel

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What unlocking Hemoptysis leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13