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Hemoptysis

AchievementRepentanceUnlock unknown

Achievement details

Achievement number: 591
Description: ???
Requirement: Defeat Delirium as Tainted Azazel

How do you unlock Hemoptysis?

In The Binding of Isaac, Hemoptysis is unlocked by earning the Delirium completion mark as Tainted Azazel.

Structured pathSource-backed requirements are mapped into trackable steps.

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Tainted Azazel → Delirium (normal)
1. Defeat Hush to unlock The Void. source
2. A Void portal can appear after a major boss; defeating Hush guarantees one. source
3. Defeat Delirium, the main boss of The Void. source
- Tainted Azazel
  - The Benighted
    How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Azazel

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What unlocking Hemoptysis leads to

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13