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The Soul

ItemRebirthLocked

passiveGame ID 335★★★★

How do you unlock The Soul?

In The Binding of Isaac, The Soul is unlocked by earning the The Lamb completion mark as The Lost (Character).

Structured pathSource-backed requirements are mapped into trackable steps.

Grants two Soul Hearts. Isaac gains a pulsing aura that repels enemies and projectiles.

See the full unlock path for The Soul — 9 steps

The Soul (Achievement)
- The Lost (Character) → The Lamb (normal)
  1. Defeat Satan 5 times to unlock The Negative. source
  2. The Negative is a guaranteed drop from Mom; take it, then defeat Satan in Sheol and touch the chest to enter Dark Room. source
  3. Find and defeat The Lamb in Dark Room. source
  - The Lost (Character)

Show full path Show missing

What unlocking The Soul leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13