Progression route

The Path to Holy Card

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7 requirements remaining11%

Path progress

Paths end with clear instructions for actions that cannot be tracked automatically.

Next steps

Isaac (Character) → The Lamb (normal)
1. Defeat Satan 5 times to unlock The Negative. source
2. The Negative is a guaranteed drop from Mom; take it, then defeat Satan in Sheol and touch the chest to enter Dark Room. source
3. Find and defeat The Lamb in Dark Room. source
Missing Poster (Achievement)
Missing Poster (Trinket)

Holy Card (Achievement)

The Lost → Delirium

How to reach Delirium: Defeat Hush to unlock The Void. A Void portal can appear after a major boss; defeating Hush guarantees one. Defeat Delirium, the main boss of The Void.

The Lost (Character)

The Lost (Achievement)

All of

Missing Poster (Trinket)

Missing Poster (Achievement)

Isaac → The Lamb

How to reach The Lamb: Defeat Satan 5 times to unlock The Negative. The Negative is a guaranteed drop from Mom; take it, then defeat Satan in Sheol and touch the chest to enter Dark Room. Find and defeat The Lamb in Dark Room.

Isaac (Character)

Die in a Sacrifice Room with Missing Poster

React Flow