Progression route

The Path to Karma

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The path to unlock Karma in The Binding of Isaac has 5 steps.

5 requirements remaining0%

Path progress

Paths end with clear instructions for actions that cannot be tracked automatically.

Next steps

Donate coins to the Greed Donation Machine: 1000
Keeper (Achievement)
Keeper (Character)

Karma (Trinket)

Karma (Achievement)

Keeper → The Lamb

How to reach The Lamb: Defeat Satan 5 times to unlock The Negative. The Negative is a guaranteed drop from Mom; take it, then defeat Satan in Sheol and touch the chest to enter Dark Room. Find and defeat The Lamb in Dark Room.

Keeper (Character)

Keeper (Achievement)

Donate coins to the Greed Donation Machine (0/1000)

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