Progression route

The Path to Soul of Isaac

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Path progress

Paths end with clear instructions for actions that cannot be tracked automatically.

Next steps

The Broken
How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Isaac
Tainted Isaac
Tainted Isaac → Hush (normal)
1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
3. Defeat Hush in Blue Womb. source

Soul of Isaac (Rune)

Soul of Isaac (Achievement)

All of

Tainted Isaac → Hush

How to reach Hush: Defeat Mom's Heart for the 10th time to unlock Blue Womb. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. Defeat Hush in Blue Womb.

Tainted Isaac

The Broken

How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Isaac

Tainted Isaac → Boss Rush

React Flow