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Soul of Apollyon

RuneRepentanceLocked

How do you unlock Soul of Apollyon?

In The Binding of Isaac, Soul of Apollyon is unlocked by earning every normal-mode completion mark as Tainted Apollyon.

Structured pathSource-backed requirements are mapped into trackable steps.

Spawns 15 random locusts.

See the full unlock path for Soul of Apollyon — 5 steps

Soul of Apollyon (Achievement)
- All of
  - Tainted Apollyon → Hush (normal)
    1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
    2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
    3. Defeat Hush in Blue Womb. source
  - Tainted Apollyon → Boss Rush (normal)

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What unlocking Soul of Apollyon leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13