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Soul of Lilith

RuneRepentanceLocked

How do you unlock Soul of Lilith?

In The Binding of Isaac, Soul of Lilith is unlocked by earning every normal-mode completion mark as Tainted Lilith.

Structured pathSource-backed requirements are mapped into trackable steps.

Grants one permanent familiar from the Baby Shop. Can give familiars that Isaac already has.

See the full unlock path for Soul of Lilith — 5 steps

Soul of Lilith (Achievement)
- All of
  - Tainted Lilith → Hush (normal)
    1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
    2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
    3. Defeat Hush in Blue Womb. source
  - Tainted Lilith → Boss Rush (normal)

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What unlocking Soul of Lilith leads to

Nothing depends on this yet.

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13