Tainted Lilith
RepentanceTaintedLockedHow do you unlock Tainted Lilith?
In The Binding of Isaac, Tainted Lilith is unlocked by unlocking The Harlot.
Structured pathSource-backed requirements are mapped into trackable steps.
Unlocked by using the Red Key, Cracked Key, or Soul of Cain to open the hidden closet in Home while playing as Lilith.
How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Lilith
Completion marks
Mom's Heart or It Lives!
Isaac
???
Satan
The Lamb
Mega Satan
Boss Rush
Hush
Ultra Greed
Delirium
Mother
The Beast
What unlocking Tainted Lilith leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13