
The High Priestess
AchievementRepentanceUnlock unknown
Achievement details
- Achievement number
- 526
- Description
- ???
- Requirement
- Defeat Ultra Greedier as Tainted Lilith
How do you unlock The High Priestess?
In The Binding of Isaac, The High Priestess is unlocked by earning the Ultra Greedier completion mark as Tainted Lilith on hard mode.
Structured pathSource-backed requirements are mapped into trackable steps.
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How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Lilith
What unlocking The High Priestess leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13