Locust of Conquest
TrinketAfterbirth+Locked
How do you unlock Locust of Conquest?
In The Binding of Isaac, Locust of Conquest is unlocked by earning the Boss Rush completion mark as Apollyon (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Upon entering a room with enemies, spawns 1-4 White Locusts which damage enemies.
See the full unlock path for Locust of Conquest — 5 stepsWhat unlocking Locust of Conquest leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13