
Locust of Death
TrinketAfterbirth+Locked
How do you unlock Locust of Death?
In The Binding of Isaac, Locust of Death is unlocked by earning the The Lamb completion mark as Apollyon (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Upon entering a room with enemies, spawns a Black Locust that does a very high amount of damage.
See the full unlock path for Locust of Death — 5 stepsWhat unlocking Locust of Death leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13