Locust of Famine
TrinketAfterbirth+Locked
How do you unlock Locust of Famine?
In The Binding of Isaac, Locust of Famine is unlocked by earning the ??? completion mark as Apollyon (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Upon entering a room with enemies, spawns a Yellow Locust that damages and slows enemies.
See the full unlock path for Locust of Famine — 5 stepsWhat unlocking Locust of Famine leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13