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Hypercoagulation

AchievementRepentanceUnlock unknown

Achievement details

Achievement number: 585
Description: ???
Requirement: Defeat Delirium as Tainted Magdalene

How do you unlock Hypercoagulation?

In The Binding of Isaac, Hypercoagulation is unlocked by earning the Delirium completion mark as Tainted Magdalene.

Structured pathSource-backed requirements are mapped into trackable steps.

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Tainted Magdalene → Delirium (normal)
1. Defeat Hush to unlock The Void. source
2. A Void portal can appear after a major boss; defeating Hush guarantees one. source
3. Defeat Delirium, the main boss of The Void. source
- Tainted Magdalene
  - The Dauntless
    How to unlock: Use Red Key (etc.) to open the hidden closet in Home as Magdalene

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What unlocking Hypercoagulation leads to

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13