
Immaculate Conception
AchievementAfterbirthUnlock unknown
Achievement details
- Achievement number
- 222
- Description
- Unlocked a new item.
- Requirement
- Complete the Boss Rush as Lilith
How do you unlock Immaculate Conception?
In The Binding of Isaac, Immaculate Conception is unlocked by earning the Boss Rush completion mark as Lilith (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Unlocked a new item.
See the full unlock path for Immaculate Conception — 6 stepsWhat unlocking Immaculate Conception leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13