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Karma

AchievementAfterbirthUnlock unknown

Achievement details

Achievement number: 239
Description: Unlocked a new item.
Requirement: Defeat The Lamb as Keeper

How do you unlock Karma?

In The Binding of Isaac, Karma is unlocked by earning the The Lamb completion mark as Keeper (Character).

Structured pathSource-backed requirements are mapped into trackable steps.

Unlocked a new item.

Keeper (Character) → The Lamb (normal)
1. Defeat Satan 5 times to unlock The Negative. source
2. The Negative is a guaranteed drop from Mom; take it, then defeat Satan in Sheol and touch the chest to enter Dark Room. source
3. Find and defeat The Lamb in Dark Room. source
- Keeper (Character)
  - Keeper (Achievement)

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What unlocking Karma leads to

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13