Pica Run
AchievementRepentanceUnlock unknown
Achievement details
- Achievement number
- 512
- Description
- Unlocked a new challenge.
- Requirement
- Defeat Mom's Heart 11 times and unlock Marbles
How do you unlock Pica Run?
In The Binding of Isaac, Pica Run is unlocked by reaching 11 defeat mom's heart or it lives! and unlocking Marbles (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Unlocked a new challenge.
- All of
- Defeat Mom's Heart or It Lives! (0/11)
How to unlock: Use 5 Gulp! pills in one run
What unlocking Pica Run leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13