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Soul of Cain

AchievementRepentanceUnlock unknown

Achievement details

Achievement number: 620
Description: ???
Requirement: Defeat Hush and Boss Rush as Tainted Cain

How do you unlock Soul of Cain?

In The Binding of Isaac, Soul of Cain is unlocked by earning every normal-mode completion mark as Tainted Cain.

Structured pathSource-backed requirements are mapped into trackable steps.

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All of
- Tainted Cain → Hush (normal)
  1. Defeat Mom's Heart for the 10th time to unlock Blue Womb. source
  2. Defeat Mom's Heart or It Lives! within 30 minutes and enter the door to Blue Womb. source
  3. Defeat Hush in Blue Womb. source
  - Tainted Cain
- Tainted Cain → Boss Rush (normal)
  - Tainted Cain

Show full path Show missing

What unlocking Soul of Cain leads to

Source: bindingofisaacrebirth.wiki.gg

Imported 2026-09-13