Eve
RebirthLockedHow do you unlock Eve?
In The Binding of Isaac, Eve is unlocked by unlocking Eve (Achievement).
Structured pathSource-backed requirements are mapped into trackable steps.
Unlocked by clearing 2 floors in a row without picking up any hearts.
How to unlock: Don't pick up any hearts for 2 floors in a row
Completion marks
Mom's Heart or It Lives!
Isaac
???
Satan
The Lamb
Mega Satan
Boss Rush
Hush
Ultra Greed
Delirium
Mother
The Beast
What unlocking Eve leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13