
Ice Cube
TrinketRepentanceLocked
How do you unlock Ice Cube?
In The Binding of Isaac, Ice Cube is unlocked by unlocking Pica Run (Challenge).
Structured pathSource-backed requirements are mapped into trackable steps.
Adds a chance to petrify enemies when entering the room. Killing the petrified enemy freezes it.
See the full unlock path for Ice Cube — 5 stepsWhat unlocking Ice Cube leads to
Nothing depends on this yet.
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13