Black Rune
AchievementAfterbirth+Unlock unknown
Achievement details
- Achievement number
- 309
- Description
- Unlocked a new item.
- Requirement
- Defeat Ultra Greedier as Apollyon
How do you unlock Black Rune?
In The Binding of Isaac, Black Rune is unlocked by earning the Ultra Greedier completion mark as Apollyon (Character) on hard mode.
Structured pathSource-backed requirements are mapped into trackable steps.
Unlocked a new item.
What unlocking Black Rune leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13