Guppy's Eye
AchievementRepentanceUnlock unknown
Achievement details
- Achievement number
- 444
- Description
- Complete the Corpse with Cain.
- Requirement
- Defeat Mother as Cain
How do you unlock Guppy's Eye?
In The Binding of Isaac, Guppy's Eye is unlocked by earning the Mother completion mark as Cain (Character).
Structured pathSource-backed requirements are mapped into trackable steps.
Complete the Corpse with Cain.
- Defeat Hush 3 times to unlock A Secret Exit. source
- After A Secret Exit is unlocked, a locked door to Downpour appears after completing Basement/Cellar/Burning Basement I or II. source
- Collect Knife Piece 1 in Downpour/Dross II. source
- Collect Knife Piece 2 in Mines/Ashpit II. source
- After defeating Mom in Mausoleum/Gehenna II, stab the flesh door that appears with the knife familiar to open it. source
- Defeat the Mausoleum version of Mom's Heart behind the flesh door, then reach Corpse II and defeat Mother. source
How to unlock: Hold 55 Coins at one time
What unlocking Guppy's Eye leads to
Source: bindingofisaacrebirth.wiki.gg
Imported 2026-09-13